It is possible to have an allergic reaction to Suboxone, but it is rare. Most allergies or adverse effects are minimal or absent when Suboxone is taken appropriately.
If you have any adverse reactions, contact the doctor who prescribed your Suboxone immediately.
The active ingredients in Suboxone are buprenorphine and naloxone. Inactive ingredients include maltitol, polyethylene oxide, acesulfame potassium, hydroxypropyl methylcellulose, citric acid, lime flavor, sodium citrate, white ink, and FD&C yellow #6.
Though rare, it’s possible to have an allergy or adverse reaction to one of the active or inactive ingredients in Suboxone.
A buprenorphine allergy generally manifests as hives, a rash, and itchiness. However, most people who are allergic to buprenorphine are allergic to all opioids. Therefore, if have taken opioids prior without an allergic reaction, it is very unlikely for you to have a true allergy to buprenorphine.
In very rare cases, just like any other medication, a systemic reaction can result, which includes anaphylactic shock, trouble breathing, low blood pressure, or loss of consciousness.
If you experience any adverse reactions, contact a doctor immediately. Systemic reactions require emergency medication attention.
An allergic reaction to naloxone is also extremely uncommon, but as with any medication, it is possible. Signs of a naloxone allergic reaction include swelling of the lips, throat, and face as well as hives.
If you experience any swelling or hives, seek emergency medical attention.
No, allergic reactions to Suboxone are extremely rare. Patients with a known hypersensitivity to buprenorphine or naloxone should not take Suboxone.
If you suspect you have a hypersensitivity to either ingredient, talk to your doctor about another form of Medication for Addiction Treatment (MAT) that would work for you. For example, if you are allergic to naloxone, you could take Subutex instead, which only contains buprenorphine.
Having a side effect from a medication is very different from having an “allergy”. Side effects are uncomfortable but rarely life threatening. Here are the most common side effects associated with Suboxone and how they can be managed. Most side effects are short term when the medication is first started and usually do improve on their own once the body gets used to the medication. However, if they do persist, there are some treatments available: