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Can I have an allergic reaction to Suboxone?

Most allergies or adverse effects are minimal or absent when Suboxone is taken appropriately.

Below, we list the most common side effects associated with Suboxone and how these can be managed. If you have any adverse reactions, you should contact your Suboxone-prescribing doctor immediately.

Most Common Side Effects How to Manage Side Effect
Headaches Aspirin, ibuprofen, acetaminophen (if there are no contraindications)
Nausea Consider spitting your saliva out after Suboxone is absorbed (rather than swallowing it); your doctor can prescribe anti-nausea medication
Constipation -Stay well hydrated (with water! aim for at least 8-10 cups/day)
-Eat a high-fiber diet (fruits, vegetables, beans/legumes, choose whole wheat and brown rice over white flour/white rice products).
-Your doctor can also prescribe you constipation medications
Dry mouth; this can lead to gum and teeth infections -Stay well hydrated (with water! aim for at least 8-10 cups/day)
-Avoid sugary drinks like sodas and juices.
-Maintain good oral hygiene (brush and floss).

Randi Sokol, MD, MPH, MMedEd

Randi Sokol, MD, MPH, MMedEd, is an Assistant Professor at the Tufts Family Medicine Residency Program and Instructor at Harvard Medical School. She is Board Certified in both Family Medicine and Addiction Medicine. She earned her B.A. at the University of Pennsylvania, her Medical Degree and Masters in Public Health from Tulane University, completed Family Medicine Residency at UC-Davis, and earned a Masters in Medical Education through the University of Dundee.

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