Yes, you can take a standard dose of Tylenol while you're using Suboxone.
The U.S. Food and Drug Administration requires drug manufacturers to list known medication interactions. Suboxone’s manufacturer does not include Tylenol in its known drug/drug interactions list.
While you can take an occasional dose of a painkiller like Tylenol to ease an occasional twinge or ache, never use medications like this regularly without talking to your doctor first. And if you’re tempted to take more Tylenol than the manufacturer recommends, talk with your doctor.
Tylenol comes in two formulations: Tylenol and Tylenol PM. Both are painkillers, and both aren’t known to interact with Suboxone.
If your pain keeps you from sleeping, Tylenol PM may seem like a good choice. This over-the-counter solution contains an antihistamine, which can make some people feel sleepy. While it is still generally safe to take while you are on Suboxone, it may make you feel even more sleepy when used in combination with Suboxone, which can also be sedating. Talk to your doctor about whether its ok to use Suboxone in combination with Tylenol PM.
Aches and pains are (unfortunately) a common part of life and you may need to take pain medications while on Suboxone. Most non-opioid medications are generally safe to take while on Suboxone, including Acetaminophen (Tylenol), Naproxen (Aleve), Ibuprofen (Motrin) etc.
However, there are other pain medications that are prescription medications only that may NOT be safe to take with Suboxone. The pain medications that may be hazardous to take along with Suboxone are any medications that can also cause drowsiness or sedation. These include medications like the gabapentinoids (Neurontin, Lyrica) or muscle relaxers (Tizanidine, Cyclobenzaprine, Methocarbamol, etc).
Over-the-counter medications are generally safe to take in combination with Suboxone, but if you have any doubts it is always best to talk to your doctor.
Talk with your doctor about your pain control needs while on Suboxone. Together, you can find safe combinations of drugs to use for pain while still continuing your Suboxone therapy.