If you have type 1 or type 2 diabetes, you can be treated safely with buprenorphine/naloxone (Suboxone) in most cases. No significant adverse interactions have been reported when taking Suboxone concurrently with insulin or other diabetes management medications. The one exception is diabetics who have developed severe complications such as kidney or liver failure. These should be closely monitored by their physician when on Suboxone.
Clinical research actually suggests that treating opioid use disorder with buprenorphine/naloxone (Suboxone) may have an unintended positive effect on sugar levels in certain patients.