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Can Suboxone make me sick?

Like any medication, buprenorphine/naloxone (Suboxone) has side effects — but most are relatively mild and can be managed under close medical supervision, sometimes with relief from other over-the-counter medications. Most of these side effects, if at all, will occur at the very beginning of treatment and then subside as your body adapts to the new medication. Suboxone’s most common side effects include headache, nausea, dizziness, fatigue, insomnia, excessive sweating, stomach cramps, constipation, and dry mouth. 

If a patient “feels sick” after taking buprenorphine/naloxone (Suboxone), most commonly, it is because they took Suboxone too soon after taking an opioid. This can cause “precipitated withdrawal,” which can be incorrectly mistaken as a side effect from the Suboxone itself as opposed to an unfortunate consequence of taking Suboxone too soon after using opioids. Therefore, make sure you talk to your doctor before starting Suboxone to prevent a “precipitated withdrawal.”

Lane McKenna

Lane McKenna has been a health and wellness writer for over 20 years. After graduating from Brown University (AB English), Lane spent over a decade on Wall Street West as a leading health services securities analyst. Opioid use disorder has long been one of her areas of expertise.

Elena Hill, MD, MPH

Elena Hill, MD; MPH received her MD and Masters of Public Health degrees at Tufts Medical School and completed her family medicine residency at Boston Medical Center. She is currently an attending physician at Bronxcare Health Systems in the Bronx, NY where she works as a primary care physician as well as part time in pain management and integrated health. Her clinical interests include underserved health care, chronic pain and integrated/alternative health.

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Lane McKenna

Lane McKenna has been a health and wellness writer for over 20 years. After graduating from Brown University (AB English), Lane spent over a decade on Wall Street West as a leading health services securities analyst. Opioid use disorder has long been one of her areas of expertise.

Elena Hill, MD, MPH

Elena Hill, MD; MPH received her MD and Masters of Public Health degrees at Tufts Medical School and completed her family medicine residency at Boston Medical Center. She is currently an attending physician at Bronxcare Health Systems in the Bronx, NY where she works as a primary care physician as well as part time in pain management and integrated health. Her clinical interests include underserved health care, chronic pain and integrated/alternative health.

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