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Can Suboxone cause high blood pressure?

High blood pressure is not listed as a common side effect of Suboxone (buprenorphine/naloxone), but low blood pressure sometimes is.

Other common adverse effects of Suboxone include:

  • Constipation
  • Headache
  • Nausea, and vomiting
  • Dizziness
  • Drowsiness and fatigue
  • Sweating
  • Dry mouth
  • Generalized muscle aches and cramps
  • Insomnia
  • Fever
  • Blurred vision 
  • Dilated pupils
  • Tremors
  • Feelings of a skipped heart beat
  • Attentional problems
  • Respiratory suppression
  • Overdose if taken in excess or with other sedating medications
  • Euphoria, misuse, addiction (possible, but lower than other opioids)
  • Withdrawal symptoms upon discontinuation
  • Precipitated opioid withdrawal (if other opioids are present in the system)

Why did my blood pressure increase when I started Suboxone?

Buprenorphine is an opioid agonist that activates the brain opioid receptors. It can also trigger opioid withdrawal if taken while there are other opioids present in the system such as heroin, fentanyl, methadone, codeine, oxycodone. 

Some opioids can last for days in the system. Blood pressure increases are commonly seen during withdrawal from opioids. 

If you experienced blood pressure increases when you started Suboxone, it will likely be short-lived. Always consult your provider before taking Suboxone, and take it only as prescribed.

Claire Wilcox, MD

Claire Wilcox, MD, is a general and addiction psychiatrist in private practice and an associate professor of translational neuroscience at the Mind Research Network in New Mexico; and has completed an addictions fellowship, psychiatry residency, and internal medicine residency. Having done extensive research in the area, she is an expert in the neuroscience of substance use disorders. Although she is interested in several topics in medicine and psychiatry, with a particular focus on substance use disorders, obesity, eating disorders, and chronic pain, her primary career goal is to help promote recovery and wellbeing for people with a range of mental health challenges.

Is Suboxone treatment a fit for you?

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Claire Wilcox, MD

Claire Wilcox, MD, is a general and addiction psychiatrist in private practice and an associate professor of translational neuroscience at the Mind Research Network in New Mexico; and has completed an addictions fellowship, psychiatry residency, and internal medicine residency. Having done extensive research in the area, she is an expert in the neuroscience of substance use disorders. Although she is interested in several topics in medicine and psychiatry, with a particular focus on substance use disorders, obesity, eating disorders, and chronic pain, her primary career goal is to help promote recovery and wellbeing for people with a range of mental health challenges.

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