When first starting buprenorphine/naloxone (Suboxone), one of the side effects can be nausea (although this tends to go away after a few days of your body getting used to the medication). There are a few things you can do to help get rid of nausea from Suboxone. Make sure you eat some food prior to your dose, making sure to do so at least a half-hour before so there is no food in your mouth when you dissolve your film under your tongue. Keep yourself well hydrated. There are medications like Ondansetron (“Zofran”) and other antiemetics (anti-nausea medicines) that your provider can prescribe you. In addition, there are many alternative therapies for nausea, including acupressure/acupuncture, mindfulness exercises, etc., that help alleviate symptoms of nausea.