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What can I do for headaches and head pressure while taking Suboxone?

Brittany Hoffmann-Eubanks, PharmD, MBA profile image
By Brittany Hoffmann-Eubanks, PharmD, MBA • Updated Sep 19, 2023

There are medication and non-medication treatments you can try under the supervision of your doctor for headache and/or head pressure while taking buprenorphine/naloxone (Suboxone). 

How to manage headaches and head pressure while on Suboxone

What to Do for Headaches and Head Pressure While Taking Suboxone

Medications such as acetaminophen, ibuprofen, and naproxen are generally considered safe to treat headache pain while taking Suboxone. However, certain medicines can interact with your Suboxone and cause serious harm if taken together. 

Since every person’s body and health status is different, you should always consult your Medication for Addiction Treatment (MAT) provider first before taking any prescription medications, over-the-counter medications, herbals, or supplements for your headache or head pressure. 

Besides drug therapy, there are a variety of non-drug therapy interventions you can try to help with pain relief from your headache and/or head pressure: 

  • Acupuncture/acupressure 
  • Get enough sleep at night 
  • Massage
  • Relaxation and mindfulness techniques 
  • Stay well hydrated and drink plenty of fluids 
  • Turn down the lights 
  • Warm or cold compresses 

If you are experiencing overly bothersome headaches or head pressure from taking Suboxone, follow up with your MAT provider to discuss further. 

Call 911 or seek emergency medical care if you experience any severe side-effects such as: 

  • Excessive drowsiness or difficulty waking up 
  • Fainting 
  • Irregular heart beating 
  • Mood changes 
  • Severe dizziness or lightheadedness 
  • Slow or shallow breathing

By Brittany Hoffmann-Eubanks, PharmD, MBA

Brittany Hoffmann-Eubanks, PharmD, MBA, received her Doctor of Pharmacy and Master of Business Administration degrees from Drake University College of Pharmacy and Health Sciences and completed her community pharmacy residency with Midwestern University and a ... Read More


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