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Who Makes Suboxone?

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Suboxone is manufactured by Indivior. It was previously manufactured by Reckitt Benckiser Pharmaceuticals, Inc. Reckitt Benckiser Pharmaceuticals rebranded under the name Indivior in 2014.[6] As a result, all manufacturing of Suboxone occurs under the name Indivior now.

History of Suboxone

Suboxone was originally created by Reckitt Benckiser Pharmaceuticals, Inc. The company is today known as Indivior.

The first formulation of buprenorphine for addiction treatment was known as Subutex. It only contained buprenorphine rather than Suboxone’s current formulation of buprenorphine and naloxone.[1]

Subutex was first released in France in 1995.[2]

Since Subutex was pure buprenorphine, it was prone to diversion as people attempted to misuse the medication by injecting it to get high. As a result, Reckitt created a combination medication, adding naloxone to buprenorphine as an abuse-deterrent component.[3]

If a user attempts to inject Suboxone with the goal of getting high, the naloxone will be activated, blocking the effects of the buprenorphine and preventing the patient from getting high or from overdosing.

Both Subutex and Suboxone received FDA approval in the United States in 2002.[4]

Today, Suboxone is considered the gold standard in Medication for Addiction Treatment (MAT). Suboxone works by controlling opioid withdrawal symptoms and cravings, so patients can focus on other aspects of their recovery treatment, such as therapy. 

Patients remain on Suboxone on a long-term basis, for months or years. Some patients remain on Suboxone indefinitely as it continues to support their recovery.


  1. The History of the Development of Buprenorphine as an Addiction Therapeutic. Annals of the New York Academy of Sciences. January 2012. Accessed June 2022.
  2. Buprenorphine Substitution Treatment in France: Drug Users’ Views of the Doctor-User Relationship. Social Science & Medicine. June 2007. Accessed June 2022.
  3. Naloxone for Opioid Overdose: Life-Saving Science. National Institute on Drug Abuse. June 2021. Accessed June 2022.
  4. Buprenorphine. Drug Enforcement Administration. May 2022. Accessed June 2022.
  5. Why Was Subutex Discontinued? May 2021. Accessed June 2022.
  6. Reckitt Benckiser Pharmaceuticals Inc. Announces Plans to Rebrand Under Indivior PLC Following Demerger. PR Newswire. October 2014. Accessed June 2022.

Elena Hill, MD, MPH

Elena Hill, MD; MPH received her MD and Masters of Public Health degrees at Tufts Medical School and completed her family medicine residency at Boston Medical Center. She is currently an attending physician at Bronxcare Health Systems in the Bronx, NY where she works as a primary care physician as well as part time in pain management and integrated health. Her clinical interests include underserved health care, chronic pain and integrated/alternative health.

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