How to Safely Detox From Demerol: Professional Treatment

Peter Manza, PhD
Reviewed By Peter Manza, PhD • Updated Aug 14, 2023 • Cited resources

Table of Contents

Safely detoxing from Demerol involves the use of Medication for Addiction Treatment (MAT), which can effectively manage symptoms of opioid withdrawal and cravings for opioid misuse.

Demerol detox typically includes professional medical supervision, personalized treatment plans, and supportive therapies to address physical and psychological aspects of the process.

If you’ve only been using Demerol as prescribed for a prolonged period, you will likely taper your dose of the drug under medical supervision. Your doctor will advise you on how to gradually lower your dose. If you’ve been misusing Demerol or have an opioid use disorder (OUD), MAT is recommended.

The goal of Demerol detox is to ensure a safe and comfortable withdrawal experience while laying the foundation for long-term recovery and minimizing the risk of relapse.

How Long Does It Take to Detox From Demerol?

Detox from Demerol, known generically as meperidine, can vary based on factors like metabolism, dosage, duration of use and overall health. If you participate in MAT, you won’t experience this detox process since medications like Suboxone keep withdrawal at bay.

Everyone is different in terms of how they will experience certain symptoms and how long those symptoms last. In general, the Demerol detox timeline will look like this:[1]

  • Days 1–3: Within 24 to 72 hours after the last Demerol dose, acute withdrawal symptoms may emerge. These can include anxiety, restlessness, irritability, muscle aches, sweating and trouble sleeping.
  • Days 4–7: Withdrawal symptoms may peak during this period. The intensity and duration vary. Common symptoms include nausea, vomiting, diarrhea, abdominal cramps, dilated pupils, goosebumps and increased heart rate.
  • Days 8–14: By the second week, acute withdrawal symptoms usually start to subside. Some people may still experience mood swings, cravings and discomfort. For many, emotional symptoms like depression or anxiety may persist and need more time to resolve.
  • Weeks 3 and beyond: At this point, physical withdrawal symptoms have significantly diminished or disappeared. However, psychological symptoms like cravings and mood disturbances may linger for weeks or months, which is why ongoing support and treatment are essential.

DaySymptomsIntensity1-3Anxiety, irritability, sweating, muscle aches, sleep disturbancesModerate4-7Nausea, vomiting, diarrhea, stomach cramps, goosebumpsSevere / symptoms peak8-14Mood swings, cravings, depression, anxietyMild, acute symptoms dissipateWeeks 3 and beyondInsomnia, cravings, mood disturbancesProtracted withdrawal symptoms linger

Is Detox From Demerol Dangerous?

Detox from Demerol can present risks and challenges, especially when attempted without medical supervision or professional guidance.

Abrupt cessation of Demerol use after prolonged use can trigger withdrawal symptoms. In some cases, these symptoms can become severe, although they are rarely life-threatening.

However, attempting Demerol detox alone can increase the risk of relapse or complications due to inadequate support and medical care.[2]

How to Detox From Demerol

Detoxing from Demerol should be done under the supervision of medical professionals to ensure the safety and efficacy of treatment.

There are three primary options for detoxing from Demerol: seeking treatment at a specialized facility, undergoing detox at a detox center, or participating in MAT. If you choose MAT, you can often do this on an outpatient basis and even utilize telehealth services for this.

Treatment Facility

  • Inpatient treatment: This option involves staying at a residential treatment facility where you receive round-the-clock care and support. Medical professionals will assess your condition, create a treatment plan just for you, and monitor your progress closely throughout the detox process.
  • Medical supervision: The treatment facility will provide medical supervision to manage withdrawal symptoms. They may administer medications to alleviate discomfort and ensure a smoother detox process.
  • Therapeutic support: Alongside medical care, treatment facilities offer various therapeutic interventions, such as individual counseling, group therapy and holistic approaches like mindfulness and yoga. These therapies address the psychological and emotional aspects of OUD.

Detox Center

  • Outpatient detox: A detox center offers outpatient services where you visit the center regularly for medical checkups, counseling sessions and medication management. This option allows you to detox off Demerol while continuing to live at home and maintain your daily responsibilities.
  • Medical assessment: Upon entering the detox center, healthcare professionals will evaluate your condition, medical history and the severity of your OUD to develop an appropriate detox plan.
  • Counseling and support:Alongside medical care, detox centers often provide counseling services to address the psychological aspects of OUD. Individual therapy and support groups can assist people in gaining a stronger understanding of their triggers, learning how to develop coping strategies and laying the foundation for long-term recovery.

MAT

  • Medication for Addiction Treatment: While many detox centers may use MAT to ease withdrawal symptoms and cravings, this treatment is also available in a variety of other settings.[3] This approach involves using specific medications under medical supervision to avoid withdrawal and increase the likelihood of successful outcomes. The popularity of MAT via telehealth services has grown in recent years.[4]

Tips to Help Opioid Detox

Demerol detox is not easy, but there are some things you can do to make your experience easier, including these:

  • Seek expert guidance. Consult with addiction treatment specialists who specialize in opioid detox. Their expertise and support will be invaluable throughout your journey, especially when you are struggling.
  • Choose MAT. With MAT, you can avoid the traditional detox process. You won’t experience withdrawal symptoms or strong opioid cravings.
  • Choose gradual reduction if OUD is not present. Gradually decrease your Demerol dosage as advised by medical professionals. This step-by-step approach helps to minimize withdrawal symptoms and eases the transition, but it should only be done under a doctor’s supervision. Medical professionals will know when to continue to decrease the dose and when to pause at a certain level until symptoms subside. 

    If you have OUD, a treatment regimen that includes MAT is recommended instead of this tapered approach to detox.
  • Take care of yourself. Focus on self-care by staying hydrated, eating nutritious meals and engaging in light exercise that get you out of the house and moving. Taking care of your physical health will help you to feel better physically and mentally during the Demerol detox process.
  • Try stress relief techniques. Incorporate stress reduction techniques into your daily routine, such as mindfulness exercises or engaging in hobbies that bring you joy.[5] These activities help to alleviate anxiety that is common during the detox process and promote relaxation.
  • Create a positive environment. Remove triggers and substances that may hinder your progress, and cultivate a home environment that encourages your recovery goals and reinforces your commitment to a healthier lifestyle. That means surrounding yourself with positive people, avoiding exposure to substances or people who use them, and focusing on moving forward.
  • Follow medical advice. Stick to the recommendations and guidelines provided by healthcare professionals rather than second guessing your treatment team or trying to pick and choose from the advice they give you. Clear communication will help you to address any concerns or questions you have and get personalized advice that fits your needs. 

The Dangers of Quitting Demerol Cold Turkey

Cold turkey is a term that refers to the practice of abruptly stopping the use of Demerol without any medical guidance, medication, or support. While it may seem like the quickest and cheapest option, the truth is that this can be dangerous and even deadly. 

Cold-turkey Demerol detox can mean the following:

  • Severe withdrawal symptoms:Rapid demerol detox can trigger intense physical and psychological withdrawal symptoms, such as nausea, vomiting, sweating, muscle aches, anxiety, insomnia and even seizures. Quitting cold turkey without medical supervision can make these symptoms overwhelming, which is unnecessary given that there are medications like Suboxone that can make these symptoms more manageable.
  • Increased risk of relapse: The discomfort and intensity of withdrawal symptoms during a cold-turkey detox can be overwhelming, leading people to relapse in order to alleviate the distress. It can further reinforce the cycle of misuse and hinder progress toward recovery.

    In some cases, it can be deadly. Relapsing after a period of abstinence is very often the circumstance under which people die due to Demerol overdose.
  • Medical complications: Quitting Demerol abruptly without medical supervision may lead to severe complications, especially if you have underlying health conditions. Withdrawal symptoms can be unpredictable, and some people may experience more severe reactions that require immediate medical attention. Medically supervised detox can help to ensure that you get treatment quickly.
  • Mental health challenges: Demerol withdrawal can significantly impact your mental health, leading to increased anxiety, depression and emotional instability.[6] Without professional support, managing these challenges can be extremely difficult and may increase the risk of relapse or other negative outcomes.
  • Lack of support and guidance: Going cold turkey often means foregoing the support, guidance and expertise of healthcare professionals who can tailor a personalized detox plan. Their expertise in managing withdrawal symptoms, providing medications, and addressing individual needs significantly improves the detox experience and increases the chances of successful and lasting recovery.

The Difference MAT Makes in Demerol Detox & Withdrawal

Early recovery from Demerol misuse can be a challenging journey, but there are strategies available to make it more manageable. Medication for Addiction Treatment can be a game changer in making the process easier and more sustainable. 

Suboxone is a combination medication that features both buprenorphine and naloxone, and this is what we offer here at Bicycle Health.[7] Buprenorphine, a partial opioid agonist, attaches to opioid receptors and quells withdrawal symptoms while naloxone, an opioid receptor antagonist, works to prevent misuse and accidental overdose. 

This combination makes Suboxone a vital medication in helping people in recovery to not only manage withdrawal symptoms but also avoid relapse. Suboxone treatment should not be navigated without the support of a healthcare professional who can monitor progress, adjust the medication as needed and provide the necessary behavioral therapies to address the underlying factors contributing to the continued substance misuse.[8]

Suboxone is a key piece in a comprehensive Demerol detox and addiction treatment plan that forms the foundation for a new life in recovery. Contact us today to learn if our program might be a good fit for your situation.

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Reviewed By

Peter Manza, PhD

Peter Manza, PhD received his BA in Psychology and Biology from the University of Rochester and his PhD in Integrative Neuroscience at Stony Brook University. He is currently working as a research scientist in Washington, DC. His research focuses on the role of the brain dopamine system in substance use disorders and in aging. He also studies brain function in obesity and eating disorders.

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  3. Information About Medication Assisted Treatment (MAT). U.S. Food and Drug Administration. https://www.fda.gov/drugs/information-drug-class/information-about-medication-assisted-treatment-mat. May 2023. Accessed May 2023.
  4. Telehealth-Based Delivery of Medication-Assisted Treatment for Opioid Use Disorder: a Critical Review of Recent Developments. Current Psychiatry Reports. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9326140/. July 2022. Accessed May 2023.
  5. Six Relaxation Techniques to Reduce Stress. Harvard Health Publishing. https://www.health.harvard.edu/mind-and-mood/six-relaxation-techniques-to-reduce-stress. February 2022. Accessed May 2023.
  6. Mental Health and Substance Use Co Occurring Disorders. Substance Abuse and Mental Health Services Administration. https://www.samhsa.gov/mental-health/mental-health-substance-use-co-occurring-disorders. April 2023. Accessed May 2023.
  7. Utilizing Buprenorphine-Naloxone to Treat Illicit and Prescription Opioid Dependence. Neuropsychiatric Disease and Treatment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984058/. April 2014. Accessed May 2023.
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