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Does your clinic ever prescribe Subutex (Bup-mono)?

A patient’s prescription is determined by their medical provider, though Bicycle Health providers primarily prescribe buprenorphine/naloxone (Suboxone). Patients who are pregnant, have severe liver disease, or a documented naloxone allergy may be prescribed buprenorphine-mono (Subutex). For patients with naloxone allergies, your Bicycle Health provider will need to coordinate care with the provider who diagnosed you with the naloxone allergy.

Buprenorphine/naloxone (Suboxone) is a combination of the active ingredient “buprenorphine” which helps prevent opioid withdrawal, craving, and overdose AND the inactive ingredient “naloxone,” which is not absorbed by the body and is added to the formulation to ensure that Buprenorphine/naloxone (Suboxone) is not misused. For example, if Buprenorphine/naloxone (Suboxone) were injected (not taken as it is supposed to),the naloxone would become active (absorbed by the body) and it could cause opioid withdrawal symptoms.

Subutex is just the active ingredient of buprenorphine.

So, Buprenorphine-naloxone (Subxone) and Buprenorphine alone (Subutex) work the same way in serving as life-saving medications for the treatment of opioid use disorder (addiction to opioid medications).

Ultimately it is up to the patient’s medical provider to determine which medication they prescribe. Most providers across the country, including those at Bicycle Health, primarily prescribe the Buprenorphine/naloxone (Suboxone) formulation.

Rebekah L. Rollston, MD, MPH

Rebekah L. Rollston, MD, MPH, is a board-certified Family Medicine Physician and Head of Research at Bicycle Health. She earned her Medical Degree from East Tennessee State University Quillen College of Medicine (in the Rural Primary Care Track) and her Master of Public Health (MPH) from The George Washington University Milken Institute School of Public Health. Dr. Rollston completed her residency at Tufts University and Cambridge Health Alliance, a Harvard-affiliated community healthcare system in Greater Boston, with emphases in addiction medicine and sexual & reproductive health. Her professional interests focus on social determinants of health & health equity, addiction medicine, gender-based violence, sexual & reproductive health, rural health, homelessness & supportive housing, and immigrant health. Dr. Rollston has published on these topics in The Lancet, Journal of Health Care for the Poor and Underserved, American Journal of Health Promotion, Journal of Appalachian Health, and Medical Care.

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Rebekah L. Rollston, MD, MPH

Rebekah L. Rollston, MD, MPH, is a board-certified Family Medicine Physician and Head of Research at Bicycle Health. She earned her Medical Degree from East Tennessee State University Quillen College of Medicine (in the Rural Primary Care Track) and her Master of Public Health (MPH) from The George Washington University Milken Institute School of Public Health. Dr. Rollston completed her residency at Tufts University and Cambridge Health Alliance, a Harvard-affiliated community healthcare system in Greater Boston, with emphases in addiction medicine and sexual & reproductive health. Her professional interests focus on social determinants of health & health equity, addiction medicine, gender-based violence, sexual & reproductive health, rural health, homelessness & supportive housing, and immigrant health. Dr. Rollston has published on these topics in The Lancet, Journal of Health Care for the Poor and Underserved, American Journal of Health Promotion, Journal of Appalachian Health, and Medical Care.

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