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Can I take Suboxone to treat depression?

No, you should not take Suboxone to treat depression. Although there is some evidence that suggests low-dose buprenorphine may help treatment-resistant depression, it is not an FDA-approved indication and requires more robust research. 

What is depression? 

Depression, also known as major depressive disorder (MDD), is a common mental health condition that affects how a person may think or act. It is the leading cause of disability for people aged 15 to 44 in the United States and affects more than 16 million adults annually. 

People who experience depression often express feelings of sadness or a loss of interest in activities they previously enjoyed. 

Common symptoms of depression: 

  • Changes in appetite 
  • Difficulty thinking, concentrating or making decisions 
  • Feeling sad or loss of interest in previously pleasurable activities 
  • Loss of energy or increased fatigue 
  • Sleep disturbances (too little or too much sleep) 
  • Suicidal thoughts or ideation 

The above list is not all-inclusive. Also, some people who have depression do not experience every symptom listed above or may have others not listed here. 

Therefore, if you are experiencing any of the above symptoms, reach out to your doctor and schedule an appointment to be evaluated as soon as possible. 

Sometimes other physical conditions can cause similar symptoms. It is important to have a thorough evaluation to rule out any other underlying conditions.

If you are thinking about suicide or have concerns about a friend or loved one, The National Suicide Prevention Lifeline (800-273-8255) is a free, confidential service available 24/7 for anyone in need.

Brittany Hoffmann-Eubanks, PharmD, MBA

Brittany Hoffmann-Eubanks, PharmD, MBA, received her Doctor of Pharmacy and Master of Business Administration degrees from Drake University College of Pharmacy and Health Sciences and completed her community pharmacy residency with Midwestern University and a local community pharmacy.

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