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How long should you let Suboxone dissolve?

Buprenorphine/naloxone (Suboxone) is available as a tablet or film and dissolves under the tongue (sublingually). To take Suboxone effectively, remember the “Rule of 15”- do NOT smoke, eat or drink for 15 minutes before taking Buprenorphine/naloxone (Suboxone); let it dissolve under your tongue for at least 15 minutes; and, do not smoke, eat or drink for 15 minutes after taking Buprenorphine/naloxone (Suboxone). Also, while Buprenorphine/naloxone (Suboxone) dissolves under your tongue, try to refrain from talking to maximize its absorption.

Randi Sokol, MD, MPH, MMedEd

Randi Sokol, MD, MPH, MMedEd, is an Assistant Professor at the Tufts Family Medicine Residency Program and Instructor at Harvard Medical School. She is Board Certified in both Family Medicine and Addiction Medicine. She earned her B.A. at the University of Pennsylvania, her Medical Degree and Masters in Public Health from Tulane University, completed Family Medicine Residency at UC-Davis, and earned a Masters in Medical Education through the University of Dundee.

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