We encourage all patients to stay on medication-assisted treatment during pregnancy—and you can take buprenorphine/naloxone (Suboxone) OR buprenorphine-monotherapy (Subutex) while pregnant. It was initially thought in the early use of buprenorphine/naloxone (Suboxone) that the naloxone component could cross the placenta and have negative consequences for the pregnancy. However, the more experience we have with opioid dependence during pregnancy, we’ve found that the potential naloxone risk is likely overstated. Many providers still err on the side of caution, though, and prescribe buprenorphine-monotherapy (Subutex) during pregnancy. Read more about buprenorphine use during pregnancy here.