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I’ve tried methadone and I don’t like it; how do I know Suboxone will work for me?

We can’t be certain that buprenorphine/naloxone (Suboxone) will work for any patient until it is tried, but compared to methadone, buprenorphine/naloxone (Suboxone) is both safer and faster to start

Buprenorphine/naloxone (Suboxone) only takes 1-2 days to completely relieve withdrawal symptoms, whereas methadone may take weeks to achieve this same goal and often makes patients feel sleepy or sedated. So, if the reason methadone didn’t work for you is the amount of time it took to work or that it made you feel sleepy or groggy, then you’re very likely to see an improvement with buprenorphine/naloxone (Suboxone).


Rebekah L. Rollston, MD, MPH

Dr. Rollston is a Family Medicine Physician at Cambridge Health Alliance, Affiliate Editor-in-Chief of the Harvard Primary Care Blog, and Founder of Doctors For A Healthy US, LLC. She earned her Medical Degree from East Tennessee State University Quillen College of Medicine and her Master of Public Health from The George Washington University. Her professional interests focus on social influencers of health & health disparities, addiction medicine, sexual & reproductive health, homelessness & supportive housing, and rural health.

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