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Does Suboxone cause or affect mood swings?

Mood swings are not a common side effect of buprenorphine/naloxone (Suboxone). Suboxone acts in the central nervous system, but it does not tend to cause depression or anxiety, based on evidence seen in large scale trials. However, every patient is different, and if you experience significant mood changes while on Suboxone, you should address these concerns with your provider.

Elena Hill, MD, MPH

Elena Hill, MD; MPH received her MD and Masters of Public Health degrees at Tufts Medical School and completed her family medicine residency at Boston Medical Center. She is currently an attending physician at Bronxcare Health Systems in the Bronx, NY where she works as a primary care physician as well as part time in pain management and integrated health. Her clinical interests include underserved health care, chronic pain and integrated/alternative health.

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