Suboxone Treatment for Tramadol Withdrawal
RX Only: See important safety information about Suboxone

What is tramadol?
Tramadol is an opioid pain medication used to treat moderate-to-moderately severe pain, and it’s often sold under the brand name Ultram. Tramadol is a weaker opioid and does not bind as tightly to receptors in the brain; it is one-tenth the potency of morphine. Further, tramadol inhibits reuptake of the neurotransmitters serotonin and norepinephrine, thereby reducing pain perception, and ultimately mimicking the effects of SNRI antidepressants.
Online Suboxone treatment at Bicycle Health provides:
Our online clinic
- Online support groups from the privacy of your own home
- Experienced, addiction-medicine trained online Suboxone doctors who truly care
- Same day treatment
In person
- Patients often wait days-to-weeks for an in-person clinic visit
- Lots of time lost in transportation to and from the clinic visit
- Unpredictable wait times during in-person visits
- High and often unpredictable costs
Tramadol Addiction Treatment
We offer medication-assisted treatment (MAT) with buprenorphine/naloxone (Suboxone) to help patients overcome tramadol addiction and withdrawal. Our confidential services take place via telemedicine, allowing patients to seek treatment within the privacy of their own homes.
The first phase of tramadol addiction treatment with buprenorphine/naloxone (Suboxone) is the induction and stabilization phase. It’s important that patients have mild-to-moderate withdrawal symptoms prior to induction… otherwise, buprenorphine/naloxone (Suboxone) will remove tramadol from receptors in your brain, resulting in precipitated withdrawal, which is very unpleasant and dangerous. At Bicycle Health, our providers and health coaches work with you to determine how long it’ll take to reach mild-to-moderate withdrawal, as well as provide robust psychosocial and physical supports throughout the induction and stabilization phase.
You can learn more about medication-assisted treatment here.
Tramadol withdrawal symptoms & timeline
It can be scary to experience withdrawal symptoms without knowing the tramadol withdrawal timeline. Tramadol withdrawal can begin as early as a few hours after the last dose, and different people will experience different symptoms based on a variety of factors. Here’s what to expect:
Symptoms occurring between 4-30 hours after the last tramadol dose
- Muscle aches
- Restlessness
- Anxiety
- Tears
- Runny nose
- Excessive sweating
- Inability to sleep
- Yawning
- Fatigue
Symptoms occurring between 30-72 hours after the last tramadol dose
- Diarrhea
- Abdominal cramping
- Goosebumps on skin
- Nausea and vomiting
- Blurry vision
- Rapid heartbeat
- High blood pressure
Tramadol withdrawal symptoms are uncomfortable, but there are withdrawal treatments your Bicycle Health provider can prescribe to help relieve these symptoms:
- Clonidine helps reduce anxiety, irritability, muscle aches, sweating, and runny nose;
- Hydroxyzine (Atarax) helps relieve anxiety and insomnia;
- Tizanidine (Zanaflex) helps reduce muscle spasms;
- Ondansetron (Zofran) relieves symptoms of nausea and vomiting;
- Loperamide (Imodium) helps relieve diarrhea; and
- Bentyl helps relieve gastrointestinal (GI) symptoms, especially abdominal cramping.
And lastly, once you start buprenorphine/naloxone (Suboxone), you will experience significant relief from tramadol withdrawal symptoms.
You may take either 4 mg, 8 mg, or 12 mg of buprenorphine on the first day of induction. You may take increasing doses in order to relieve symptoms of withdrawal. Induction may take up to 3 days, after which you’ll feel well with no further withdrawal symptoms… and finally yourself again!

How does Bicycle Health work?
Your Journey to Recovery with Bicycle Health
Here at Bicycle Health, we combine buprenorphine/naloxone (Suboxone) treatment with behavioral health supports, like online support groups and health coaches.
Learn more about how our process works here.
We are physicians, nurse practitioners, and physician assistants who are invested in your recovery.
Bicycle Health providers, staff, and leadership believe everyone deserves access to confidential, individualized, and non-judgmental care for tramadol addiction.
Schedule a call with an enrollment coordinator to learn how buprenorphine/naloxone (Suboxone) treatment can improve your tramadol withdrawal symptoms and overall quality of life.
